Opioids Dosage Conversion

Opioids by Chris Marcellino MD and Norris Vivatrat MD is an opioid analgesic dosage conversion calculator for use by trained medical professionals. The application supports conversion to and from opioids commonly prescribed and used in U.S. hospitals orally, parenterally, or transdermally, including morphine, codeine, hydromorphone, hydrocodone, fentanyl, methadone, oxycodone and oxymorphone. The application is intended to help and instruct in the process of conversion of opioid regimens.

• Native support for iPhone, iPad and iPod touch
• Multiple route support
• Multiple drug support
• Incomplete cross tolerance option
• Breakthrough dosing calculator
• Provides instructional details about each calculation
• Saves last calculation on exit
• Supports landscape and portrait modes
• Reference guide

By Professor EBM, the Internal Medicine Residency Teaching Resource for Evidence-Based Medicine: http://www.professorebm.com/, a resource of the Santa Clara Valley Medical Center.

While effort has been made to ensure that calculations are accurate and that conversion factors are in accordance with current accepted medical practices, use of this application is entirely at your own risk. This application should only be used by trained medical professionals and all results should be double checked by hand. Use of the app requires acceptance of the terms of use that are included with the application.

Please send support requests and feedback using the link in the About tab of the app, though as a free academic tool we only have limited resources to address new feature requests.

Opioid equipotency data is taken from CAPC conversion values except where noted (see the reference tab in the app.) CAPC values are as published in the Center to Advance Palliative Care Prescribing Opioids: A Reference Guide curriculum, which are adapted from McPherson ML. Demystifying Opioid Conversion Calculations: A Guide for Effective Dosing, 2nd ed. American Society of Health-System Pharmacists, Bethesda, Maryland, 2018. EPEC values are as published in EPEC-O Participants Handbook, 2005.

Chris Marcellino, MD — Mayo Clinic
Norris Vivatrat, MD — UCSD Medical Center

Special thanks to Dr. Tom Mouser (EveryStep, Des Moines, IA) and Dr. David Rand (UVM Medical Center).

更新履歴
Use traditional conversion (1:2) for fentanyl based on clinical experience and increased safety (regardless of incomplete cross tolerance) when transitioning to oral opioids from transdermal fentanyl. 

Also, includes all updates in the 3.0 version:
Changed opioid equipotency calculations to use CAPC conversion tables (which are adapted from McPherson's Demystifying Opioid Conversion Calculations...).
Simplify methadone conversion tables and remove outdated "Rule of 15" usage. Added new guidance comments for methadone initiation.
Updated reference tab documentation.